Table 1.

HPV testing among patients with oropharyngeal squamous cell carcinoma based on recoding with modified guidelines^*, Iowa, 2010-2014.

			Modified Guideline Test Results*
Tested	All		Positive		Negative		Discordant†
	No. of patients	%	No. of patients	%	No. of patients	%	No. of patients	%
Yes	450	55	328	73	96	21	26	6
p16 only	254	56	203	80	51	20	–	–
HPV-DNA only	92	20	57	62	35	38	–	–
p16 + HPV-DNA	104	23	68	65	10	10	26	25
No	374	45
Total	824

^*p16 only - if p16 (IHC) testing was the only test performed, p16-positive patients were coded as “070: HPV positive, types not stated” (n=194), or if it was stated as high risk, then the case was coded as “060: HPV positive, high-risk types, type not stated” (n=9); p16-negative patients were coded as “000: Negative” (n=51). P16 + HPV-DNA - if both p16 testing and HPV-DNA testing were performed, results were classified according to the HPV-DNA results.

^†Includes those patients that were tested for both p16 and HPV-DNA, but had discordant results (p16+, HPV-DNA-; p16-, HPV-DNA+).

Dashes indicate cells that are not applicable to those patients.

Abbreviations: HPV-Human papillomavirus; IHC-Immunohistochemistry