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Training of the Chained-Regularization approach: The first step (top, denoted as Selection Step) selects the image measurements informative for distinguishing HIV from controls, while the second step (bottom, denoted as Reweighing Step) focuses on improving the accuracy by reweighing the selected measures for classifying the samples. Note, both steps are based on the same classifier but differ in regularizing (or constraining) its parameterization.
