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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Clin Pharmacol Ther. 2018 Jul 25;104(5):933–939. doi: 10.1002/cpt.1135

Table 2.

Subjects with genotype-phenotype discordance stratified by the number of CYP2D6 dependent drugs co-ingested.

Number of
CYP2D6
dependent
drugs
0
n=12
1
n=16
2
n=8
3
n=3
Number (%)
of subjects
with
discordance
based on the
3-hour
DX/DM ratio

n=14 subjects
1 (8%) 7 (43%) 4 (50%) 2 (67%)