Table 5.
Clinical effects in those taking metoprolol predicted by phenotype, the Ki formula, and combined phenotype (PM/IM or NM/UM). Adjusted for metoprolol does.
| Univariate Analyses | ||||
|---|---|---|---|---|
|
Outcome |
Predictor |
LR Chisq |
Df |
Pr(>Chisq) |
| 10 % Blood pressure decline |
||||
| Phenotype | 4.754 | 2 | 0.090 | |
| Ki | 1.699 | 1 | 0.190 | |
| Combined Phenotype | 4.702 | 1 | 0.029* | |
| 10% Heart rate decline |
||||
| Phenotype | 3.016 | 2 | 0.175 | |
| Ki | 0.577 | 1 | 0.257 | |
| Combined Phenotype | 2.964 | 1 | 0.069 | |
| Composite of either 10% Blood pressure or HR decline |
||||
| Phenotype | 6.289 | 2 | 0.029* | |
| Ki | 0.790 | 1 | 0.273 | |
| Combined Phenotype | 5.190 | 1 | 0.020* | |