Table 1.
Low Aβ | High Aβ | Total | |
---|---|---|---|
N (% Female) | 50 (64.00) | 18 (44.44) | 68 (58.82) |
Mean Age (SD) | 66.62 (11.12)* | 74.06 (7.40) | 68.59 (10.73) |
Mean Education (SD) | 15.30 (2.68) | 16.33 (2.50) | 15.57 (2.66) |
Mean MMSE (SD) | 28.84 (0.82) | 28.83 (0.71) | 28.84 (0.78) |
Mean CESD (SD) | 3.88 (3.78) | 3.44 (3.71) | 3.77 (3.74) |
fMRI Task Accuracy | |||
0-Back (SD) | 94.00 (10.65) | 93.80 (9.90) | 98.33 (10.38) |
2-Back (SD) | 83.70 (11.92) | 83.75 (10.42) | 83.17 (11.50) |
3-Back (SD) | 76.75 (8.68) | 72.82 (5.83) | 75.71 (8.17) |
4-Back (SD) | 74.77 (7.84) | 73.01 (5.88) | 74.30 (7.37) |
fMRI Task RT (sec) | |||
0-Back (SD) | 0.68 (0.14) | 0.63 (0.07) | 0.66 (0.13) |
2-Back (SD) | 0.90 (0.20) | 0.82 (0.16) | 0.88 (0.19) |
3-Back (SD) | 1.01 (0.23) | 0.90 (0.18) | 0.98 (0.22) |
4-Back (SD) | 1.00 (0.25) | 0.88 (0.17) | 0.97 (0.23) |
EF Composite (SD) | 0.04 (0.56) | −0.09 (0.56) | 0.00 (0.56) |
WM Composite (SD) | 0.02 (0.83) | −0.06 (0.72) | 0.00 (0.80) |
Note: Low Aβ – less than 1.11 standardized uptake value ratio; High Aβ – greater than or equal to 1.11 standardized uptake value ratio. MMSE - Mini Mental State Exam; CESD – Center for Epidemiologic Study-Depression; Accuracy reported as mean percent accuracy; Response time (RT) reported as a mean of medians such that a median RT is taken across all trials in a given condition for each subject and averaged across subjects; SD – standard deviation; sec – seconds; EF – executive function; WM – working memory; both are averages of standardized test measures reported as z-scores;
p < .05.