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. 2018 Aug 1;6(4):474–476.e3. doi: 10.1016/j.jcmgh.2018.07.001

Figure 2.

Figure 2

The genetic control of gene expression is shared regardless of disease subtype and tissue profiled. (A) Histogram depicting the difference in effect size (β, in SD units) of eQTLs detected in the ileum and rectum of CD patients. Top: For eGenes detected in both the ileum and rectum, the difference in effect size of the top eQTL in each tissue (n = 824). Bottom: The difference in effect size for eQTLs significant in only 1 of the 2 tissues (n = 1204). (B) Histogram of the difference in effect size between inflamed and noninflamed biopsy specimens for 903 eQTLs detected in ileum CD (see main text).