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. 2018 Oct 16;9:2278. doi: 10.3389/fimmu.2018.02278

Figure 1.

Figure 1

CDRL1 amino acid insertion positions according to the Kabat and Chothia numbering scheme for light chain variable domains of protein databank (PDB) structures 1igm and 2imm. (A) Amino acid sequence of the 1igm and 2imm CDR1L according to the Kabat or Chothia numbering scheme. The insertion of amino acids from longer loops is placed behind L27 (magenta) and denoted by ‘27a to 27f' according to Kabat's numbering; whereas they are placed behind L30 (blue) according to Chothia's numbering scheme. The structurally aligned position L31 is shown in red. (B) Ribbon representation of the superposition of the CDRL1 loops of 1igm and 2imm from amino acids L24 to L34. The color code is as in (A) and the additional amino acids of 2imm in CDRL1 (L27a to L27f) according to Kabat numbering are shown in yellow. (C) Same structural superposition as in (B) except that the yellow colored supplementary amino acids and the blue amino acid position is according to Chothia's numbering scheme.