Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 16;9:2278. doi: 10.3389/fimmu.2018.02278

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Dondelinger, Filée, Sauvage, Quinting, Muyldermans, Galleni and Vandevenne.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Alignment of a nanobody sequence from the PDB (3dwt) according to Kabat, Chothia, and IMGT numbering schemes. In green are the cysteines forming the conserved disulphide bond packed against a conserved tryptophan. In addition the conserved tryptophan118-glycine119 (IMGT numbering, also in green) downstream of the CDR3H demarcates the start of the framework-4 region. The IMGT numbering scheme uses gaps (indicated in red), if a residue is absent at a given position. Insertion positions are indicated in blue.