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. 2018 Oct 16;8:438. doi: 10.3389/fonc.2018.00438

Table 1.

Patients descriptive characteristics.

Variables No Cancer (N = 1,559) PCa (N = 1,018) p-value ISUP 1 PCa (N = 406) p-value* ISUP>1 PCa (N = 612) p-value **
Age (years) 65 (60, 70) 68 (63, 74) <0.0001 67 (62, 72) 0.001 70 (65, 75) <0.0001
Suspicious DRE 33.8% (527) 53.7% (547) <0.0001 39.8%(162) 0.065 62.8% (384) <0.0001
PSA (ng/mL) 6 (5, 8) 7 (5, 10) 0.0002 6 (5, 8) 0.041 7 (5, 11) <0.0001
PVol (mL) 60 (44, 80) 42 (32, 57) <0.0001 47 (35, 61) <0.0001 40 (30, 55) <0.0001
PVR (mL) 40 (20, 70) 20 (1, 50) <0.0001 20 (1, 50) <0.0001 22 (1, 50) <0.0001
PFR (mL/s) 12 (8, 16) 13 (10, 17) <0.0001 14 (10, 18) <0.0001 13 (9, 17) <0.0001

Continuous variables are reported as medians (interquartile range); categorical variables are reported as rates (n).

*

ISUP 1 vs. no cancer.

**

ISUP >1 vs. no cancer. DRE, digital rectal examination; ISUP, International Society of Urological Pathology; PCa, prostate cancer; PFR, peak flow rate; PSA, prostate-specific antigen; PVol, prostate volume; PVR, post-void residual urinary volume. The bold values are the statistically significant differences.