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. 2018 Oct 16;8:438. doi: 10.3389/fonc.2018.00438

Table 2.

Univariable and multivariable binary logistic regression analysis testing the value of clinical variables in predicting Prostate Cancer (any ISUP).

Variables Univariable analysis Multivariable analysis
Odds ratio (95% C.I.) Std. Err. P > |z| Odds ratio (95% C.I.) Std. Err. P > |z|
Age (years) 1.057 (1.046–1.069) 0.006 <0.001 1.076 (1.059–1.093) 0.009 <0.001
Suspicious DRE 2.277 (1.857–2.791) 0.237 <0.001 1.852 (1.472–2.329) 0.217 <0.001
PSA (ng/mL) 1.061 (1.038–1.084) 0.012 <0.001 1.093 (1.055–1.132) 0.020 <0.001
PVol (mL) 0.970 (0.966–0.974) 0.002 <0.001 0.971 (0.966–0.976) 0.003 <0.001
PVR (mL) 0.989 (0.987–0.991) 0.001 <0.001 0.993 (0.989–0.996) 0.002 <0.001
PFR (mL/s) 1.031 (1.019–1.044) 0.006 <0.001 1.010 (0.992–1.028) 0.009 0.271

DRE, digital rectal examination; ISUP, International Society of Urological Pathology; PCa, prostate cancer; PFR, peak flow rate; PSA, prostate-specific antigen; PVol, prostate volume; PVR, post-void residual urinary volume. The bold values are the statistically significant differences.