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. 2018 Oct 11;9:2406. doi: 10.3389/fmicb.2018.02406

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Copyright © 2018 Ibáñez, Farías, Gonzalez-Troncoso, Corrales, Duarte, Retamal-Díaz and González.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Viral capsid assembly in the nucleus and transport to the cytosol. (A) γ-mRNA translation. (B) Import of capsid proteins into the nucleus. (C) Capsid Assembly. (D) Capsid Maturation. (E) Viral genome packaging. (F) Initial tegument assembly. (G) Capsid envelopment in the INM. (H) Capsid envelopment in the perinuclear space. (I) Fusion of enveloped nuclear capsids with the ONM. (J) Release of mature capsids into the cytoplasm. INM, Inner Nuclear Membrane; ONM, Outer Nuclear Membrane; NEC, Nuclear Export Complex; NLS, Nuclear Localization Sequences; ER, Endoplasmic Reticulum; TG, Trans-Golgi Network.

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