Fig. 3.

Effect of the complex cis-[PtCl(PIP-OH)(PPh₃)₂]PF₆ (CPP) in the cell viability of HL-60 cells, as determined by the trypan blue staining after 24 (A) and 48 (B) h of incubation. The white bars represent number of viable cells (x10⁴cells/mL) and the gray bars represent cell inhibition (%). The negative control (CTL) was treated with the vehicle (0.1% DMSO) used for diluting the compound tested. Doxorubicin (DOX, 2 µM) and oxaliplatin (OXA, 2.5 µM) were used as the positive controls. Data are presented as the means ± S.E.M. of three independent experiments performed in duplicate. * P < 0.05 compared with the negative control by ANOVA, followed by the Student Newman-Keuls Test.