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. 2018 Oct 15;9:831. doi: 10.3389/fneur.2018.00831

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Copyright © 2018 Liu, Chen, Kwan, Chou, Yu, Yen, Liao, Chen, Lin, Chen, Jih, Lu, Wu, Wang and Hsiao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Group difference of gamma synchronizations between PRRT2-related PKD and non-PRRT2 PKD. (A) The PKD patients with an identified PRRT2 pathological mutation (n = 5) had lower evoked peak gamma frequencies than those patients without a PRRT2 mutation (n = 9) (for the first response, PRRT2+ PKD: PRRT2- PKD = 35.8 ± 2.1 Hz: 44 ± 1.7 Hz, p = 0.028; for the second response, PRRT2+ PKD: PRRT2- PKD = 35 ± 1.9 Hz: 44.5 ± 1.4 Hz, p = 0.004). (B,C) There was no difference of the peak latency, peak power and power ratio of gamma activities between PRRT2+ PKD and PRRT2- PKD. PRRT2+ PKD = PRRT2-related PKD, PRRT2- PKD = non-PRRT2 related PKD, **p < 0.01, *p < 0.05.