Table 2.

Uni‐ and multivariate analyses of the OS in 87 CRC patients

Clinicopathological characteristics	Hazard ratio (95% CI)	P‐value	Hazard ratio (95% CI)	P‐value
	Univariate		Multivariate
Gender (female vs male)	1.414 (0.733‐2.727)	0.301	1.314 (0.640‐2.701)	0.457
Age (≤60 vs >60 y)	0.993 (0.499‐1.977)	0.984	0.778 (0.377‐1.606)	0.498
Tumor size (5≤ vs >5 cm)	2.249 (1.109‐4.560)	0.025 a	2.332 (1.066‐5.103)	0.034 a
Histology (adenocarcinoma vs mucinous carcinoma vs others)	0.650 (0.156‐2.711)	0.554	0.679 (0.158‐2.916)	0.603
	1.665 (0.399‐6.952)	0.485	3.789 (0.728‐19.729)	0.114
Tumor invasive depth (T1‐2 vs T3‐4)	1.488 (0.527‐4.201)	0.453	0.572 (0.168‐1.948)	0.372
Lymph node metastasis (N0 vs N1‐2)	3.099 (1.617‐5.940)	0.001 a	3.653 (1.769‐7.543)	<0.001 a
Distant organs metastasis (M0 vs M1)	5.622 (1.632‐19.372)	0.006 a	6.624 (1.748‐25.102)	0.005 a
LEA expression (low vs high expression)	2.389 (1.241‐4.601)	0.009 a	2.233 (1.125‐4.432)	0.022 a

CI: confidence interval.

^a P < 0.05 indicates that the lower limit of the 95% CI of hazard ratio is >1.