Table 2. Unadjusted Cox Hazard Regression Analysis, predictors of mesothelioma survival (n=888). Ref – Reference group.

Variable	Hazard ratio	95% Confidence interval p value for trend
Age
18–44	1.00	Ref
45–54	2.0	1.3-3         P=0.001
55–64	2.3	1.6-3.3      P<0.001
65–74	2.7	1.8-3.9      P<0.001
75+	3.4	2.3-5.1      P<0.001
Gender
Female	1.0	Ref
Male	1.6	1.4.0-1.9   P<0.001
Anatomic site
Peritoneum	1.0	Ref
Pleural	2.1	1.7-2.6      P<0.001
Therapy
Surgery	1.0	Ref
Surgery, chemo	0.49	0.39-0.62   P<0.001
Surgery, chemo, radiation	0.63	0.44-0.90   P=0.011
Smoking history
No	1.0	Ref
Yes	1.2	1-1.5         P=0.022
Stage (pleural cases only)
I	1.0	Ref
II	1.3	0.82-2.0    P<0.27
III	1.7	1.31-2.1    P<0.001
IV	2.0	1.24-3.2    P=0.004
Histology
Biphasic	1.0	Ref
Epithelial or epithelioid	0.48	0.40-0.57  P<0.001
Sarcomatoid	0.97	0.74-1.26  P=0.797
Race
Non European American	1.0	Ref
European American	1.8	1.1-2.8      P<0.012
Asbestos Exposure
Yes	1.0	Ref
No	0.61	0.48-0.78   P<0.001