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. 2018 Sep 10;67(11):2183–2198. doi: 10.2337/db18-0370

Figure 6.

Figure 6

HFD-induced downregulation of H19, DUSP27, and AMPK signaling in muscle. A: Results of GTTs of WT mice after 13-week exposure to RC or HFD. B: RT-qPCR results of H19 and DUSP27 expression from RC and HFD muscles. C: Representative Western blots of DUSP27, phosphorylation of AMPK (pAMPK), AMPK, pACC, ACC, and ACTB proteins from experiments shown in B. Extracts from three mice were loaded in each group. D: Quantification results of Western blots. All data are shown as mean ± SEM of four to five animals per group. *P < 0.05 and **P < 0.01, compared with the RC group. AUC, area under the curve.