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. 2018 Aug 13;67(11):2329–2336. doi: 10.2337/db18-0355

Table 4.

Association between the number of IA and each CBC measurement in 72 subjects (boys n = 42)

CBC n IAs Estimate SE P value
White blood cells (109 cells/L)
 All subjects 1 0.142 0.257 0.582
2 −0.379 0.293 0.197
3 −0.613 0.225 0.007
 Boys 1 −0.001 0.392 0.998
2 −0.701 0.404 0.086
3 −0.789 0.332 0.019
 HLA-DR3-DQ2/DR4-DQ8 1 0.512 0.401 0.203
2 −0.392 0.415 0.347
3 −0.729 0.360 0.045
Neutrophils (109 cells/L)
 All subjects 1 0.081 0.161 0.616
2 −0.328 0.178 0.068
3 −0.427 0.141 0.003
 Boys 1 0.033 0.251 0.897
2 −0.479 0.259 0.068
3 −0.634 0.216 0.004
 HLA-DR3-DQ2/DR4-DQ8 1 0.270 0.245 0.275
2 −0.420 0.246 0.091
3 −0.572 0.216 0.010
Lymphocytes (109 cells/L)
 All subjects 1 0.092 0.091 0.315
2 0.025 0.109 0.822
3 −0.175 0.0840 0.038
 Girls 1 0.080 0.124 0.519
2 0.368 0.175 0.038
3 −0.115 0.118 0.332
Monocytes (109 cells/L)
 All subjects 1 0.003 0.0244 0.885
2 −0.057 0.0281 0.044
3 −0.026 0.0214 0.231
Red blood cells (1012 cells/L)
 All subjects 1 0.019 0.080 0.813
2 −0.200 0.089 0.026
3 −0.112 0.073 0.125
 Girls 1 0.060 0.119 0.616
2 −0.471 0.142 0.002
3 −0.109 0.104 0.295
 HLA-DR3-DQ2/DR4-DQ8 1 0.029 0.129 0.826
2 −0.211 0.136 0.125
3 −0.320 0.113 0.006
Hemoglobin (g/L)
 All subjects 1 −0.031 0.210 0.882
2 −0.635 0.235 0.008
3 −0.282 0.193 0.147
 Girls 1 −0.038 0.300 0.900
2 −1.248 0.335 0.0007
3 −0.407 0.255 0.116
 HLA DR3/4-DQ2/8 1 −0.255 0.372 0.495
2 −0.614 0.388 0.116
3 −0.710 0.326 0.031
Hematocrit (L/L)
 All subjects 1 0.147 0.577 0.799
2 −1.801 0.640 0.006
3 −1.034 0.525 0.050
 Girls 1 0.395 0.907 0.664
2 −3.635 0.990 0.0007
3 −1.011 0.776 0.200
 HLA-DR3-DQ2/DR4-DQ8 1 −0.375 0.996 0.707
2 −1.922 1.029 0.065
3 −2.514 0.853 0.004
Mean corpuscular volume (fL)
 All subjects 1 0.854 0.597 0.153
2 −0.481 0.734 0.513
3 −0.351 0.544 0.519
 Boys 1 1.728 0.850 0.044
2 −0.505 0.900 0.576
3 −0.118 0.716 0.869
 Not HLA-DR3-DQ2/DR4-DQ8 1 2.210 0.826 0.008
2 −0.605 1.246 0.628
3 −0.192 0.722 0.791
MCH (pg)
 HLA-DR3-DQ2/DR4-DQ8 1 0.861 0.418 0.042
2 0.034 0.433 0.938
3 0.562 0.354 0.116

Values in boldface type are statistically significant (P < 0.05).