Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 22;17:164. doi: 10.1186/s12934-018-1010-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — Proposed cyclization mechanisms for the generation of the main STPs from Copu2 and Copu3. The reaction starts by ionization and isomerization of farnesyl diphosphate (FPP) creating nerolidyl diphosphate (NPP). The first cyclization is achieved by the formation of the C1–C10 bond. Subsequent C6–C1 bond formation yields a cadinyl cation, which represents a general precursor for various cadalane and cubebane-type STPs [14, 44–47]