Table 1.
Clinicopathological information of normal subjects and CCA patients.
| Characteristics | Normal liver n = 21 No. (%) |
Non-OV-CCA n = 98 No. (%) |
OV-CCA n = 33 No. (%) |
Statistical significance |
|---|---|---|---|---|
| Age (years) | ||||
| ≤40 | 15 (71.4) | 12 (12.2) | 2 (6.1) | ∗∗ |
| >40 | 6 (28.6) | 86 (87.8) | 31 (93.9) | |
| Sex | ||||
| Male | 12 (57.1) | 56 (57.1) | 26 (78.8) | n.s. |
| Female | 9 (42.9) | 42 (42.9) | 7 (21.2) | |
| TNM classification | ||||
| Ta | ||||
| T1 | — | 2 (2.0) | 1 (3.7) | ## |
| T2 | — | 51 (52.0) | 5 (18.5) | |
| T3 | — | 43 (43.9) | 9 (33.3) | |
| T4 | — | 2 (2.0) | 12 (44.4) | |
| Na | — | |||
| N0 | — | 67 (68.4) | 3 (20.0) | ## |
| N1 | — | 31 (31.6) | 12 (80.0) | |
| Ma | — | |||
| M0 | — | 95 (96.9) | 24 (85.7) | # |
| M1 | — | 3 (3.1) | 4 (14.3) | |
| Tumor stagea | ||||
| I | — | 2 (2.0) | 0 (0.0) | ## |
| II | — | 40 (40.8) | 3 (11.5) | |
| III | — | 27 (27.6) | 7 (26.9) | |
| IV | — | 29 (29.6) | 16 (61.6) | |
OV: Opisthorchis viverrini; CCA: cholangiocarcinoma; n.s.: not significant. ∗∗ p < 0.01 compared to that of the normal liver group. # p < 0.05 and ## p < 0.01 compared to that of the non-OV-CCA group. aPatients missing clinical information are not included in the statistical analyses.