Table 2.
Effect of CXL on VEGF, MMP-2, MMP-9, and TIMP-1 expression after corneal alkali burns.
| Group | n | Day 7 after alkali burn | Day 14 after alkali burn | ||||||
|---|---|---|---|---|---|---|---|---|---|
| VEGF | MMP-2 | MMP-9 | TIMP-1 | VEGF | MMP-2 | MMP-9 | TIMP-1 | ||
| A | 5 | 0.44 ± 0.21 | 0.42 ± 0.16 | 0.17 ± 0.14 | 0.27 ± 0.11 | 0.68 ± 0.29 | 0.63 ± 0.14 | 0.52 ± 0.29 | 0.58 ± 0.26 |
| B | 5 | 0.50 ± 0.17 | 0.45 ± 0.07 | 0.71 ± 0.09∗ | 0.60 ± 0.17 | 0.27 ± 0.12∗ | 0.31 ± 0.20∗ | 0.39 ± 0.17 | 0.42 ± 0.13 |
| C | 5 | 0.43 ± 0.16 | 0.54 ± 0.21 | 0.61 ± 0.15∗ | 0.42 ± 0.12 | 0.38 ± 0.17∗ | 0.47 ± 0.12 | 0.45 ± 0.22 | 0.37 ± 0.07 |
| D | 5 | 0.40 ± 0.27 | 0.53 ± 0.13 | 0.43 ± 0.20∗ | 0.53 ± 0.22∗ | 0.35 ± 0.08∗ | 0.40 ± 0.09∗ | 0.39 ± 0.16 | 0.46 ± 0.17 |
| E | 5 | 0.39 ± 0.19 | 0.49 ± 0.10 | 0.45 ± 0.14∗ | 0.44 ± 0.24 | 0.38 ± 0.16∗ | 0.36 ± 0.06∗ | 0.40 ± 0.14 | 0.38 ± 0.15 |
| F | 5 | 0.50 ± 0.26 | 0.51 ± 0.18 | 0.55 ± 0.14∗ | 0.58 ± 0.10∗ | 0.33 ± 0.15∗ | 0.46 ± 0.20 | 0.42 ± 0.11 | 0.53 ± 0.14 |
| F | 0.239 | 0.481 | 7.751 | 2.511 | 2.742 | 3.004 | 0.376 | 1.373 | |
| P | 0.941 | 0.787 | 0.00 | 0.058 | 0.043 | 0.03 | 0.86 | 0.27 | |
LSD-t comparison was conducted. ∗means P < 0.05 compared to Group A.