FIG. 4.

Histomorphometric parameters for bone regeneration in noncritical-size defects 4 weeks postoperatively. The formation of new bone (a) and defect bridging (b) is significantly elevated in defects treated with scaffolds compared to empty defects. Titanium and TCP scaffolds with identical architecture performed equally well in both categories. A significant increase could only be detected between the titanium and the TCP scaffolds when the latter was doped with 10 μg BMP-2. Values are displayed as box plots ranging from the 25th (lower quartile) to the 75th (upper quartile) percentile, including the median as solid black line and whiskers, showing the minimum and maximum values. Values outside the range of the box blot are shown as individual points. p Values are provided in the graphs. Color images available online at www.liebertpub.com/tea