Fig. 2.

Experimental data used for model calibration. Neonatal human dermal fibroblasts were treated with 5 ng ml^–1 TGF-β for 0, 1, 2, 4, 8 and 12 h. Shown are profiles of 6 biological replicates for (a) Smad7 and (b) Ski messenger RNA, measured by high throughput quantitative PCR as described in the methods