Table 1.
Demographic and clinical characteristics of the patients included in the analysis of predictors of mortality according to FEV1 (GOLD classification of FEV1 severity) of COPD at baseline
| Variable | Total (N=110) | COPD GOLD 1 and 2 n=53 | COPD GOLD 3 and 4 n=57 | P-value |
|---|---|---|---|---|
|
| ||||
| Male/female sex, n | 74/36 | 33/20 | 41/16 | 0.381a |
| Age, years | 65 (59–72) | 65 (59–73) | 67 (61.5–73) | 0.536b |
| SB, pack-years | 50 (35–67) | 50 (40–71.5) | 50 (30–59) | 0.173b |
| SpO2, % | 94 (92–96) | 94 (93–97) | 93 (91–95) | 0.003b |
| FEV1, % of the predicted | 52.5 (40–73) | 73 (60–87.5) | 40 (32.5–46.5) | <0.001b |
| FEV1, L | 1.20 (0.93–1.72) | 1.65 (1.32–2.14) | 0.94 (0.75–1.09) | <0.001b |
| BMI, kg/m2 | 25 (21–28) | 25.8 (21.7–31.1) | 24.4 (20.7–27.4) | 0.097b |
| Fat-free mass, kg | 42 (7) | 41.5 (7.4) | 41.9 (7.1) | 0.787c |
| mMRC, score | 1 (1–2) | 1 (1–2) | 2 (1–3) | 0.006b |
| 6MWT, m | 430 (91) | 457 (85) | 404 (89) | 0.002c |
| BODE, class | 1 (1–2) | 1 (1–1) | 2 (1–3) | <0.001b |
Notes: Parametric data are expressed as mean and SD and nonparametric data as median (IQR 25–75). The 2004 GOLD classification of airflow limitation severity – GOLD 1 or GOLD 2 vs GOLD 3 or GOLD 4 (achi-squared test, bMann–Whitney, or cunpaired t-test). BODE index: class 1 (score 0–2), class 2 (score 3 and 4), class 3 (score 5 and 6), and class 4 (score 7–10).
Abbreviations: 6MWT, 6-minute walk test; BMI, body mass index; BODE, Body mass index, airway Obstruction, Dyspnea, and Exercise capacity; SB, smoking burden; SpO2, pulse oximetry; mMRC, Modified Medical Research Council.