Table 4.
Cox regression analysis with replacement of the BODE index for the variables that compose it
| Variables | HR (95% CI), N=110 | P-value |
|---|---|---|
|
| ||
| Male | 1.36 (0.66–2.76) | 0.396 |
| Age (years) | 0.97 (0.93–1.03) | 0.434 |
| SpO2 (%) | 0.93 (0.84–1.03) | 0.170 |
| 6MWT (m) | 0.99 (0.99–1.00) | 0.305 |
| FEV1 (%) | 0.99 (0.97–1.00) | 0.417 |
| BMI >21 kg/m2 (reference) | * | * |
| BMI (≤21 kg/m2) | 2.70 (1.38–5.25) | 0.003 |
| mMRC (score) | 1.06 (0.75–1.50) | 0.730 |
| CCI | 1.29 (0.99–1.68) | 0.057 |
| Exacerbation (n) | 1.38 (1.03–1.85) | 0.027 |
Notes: All variables were included together in the Cox proportional hazard regression (sex, age, SpO2, 6MWT, BMI, mMRC, CCI, and number of exacerbations in first 3 years). Exacerbation, number of exacerbations per patient in the 3-year period.
Abbreviations: 6MWT, 6-minute walk test; BMI, body mass index; BODE, Body mass index, airway Obstruction, Dyspnea, and Exercise capacity; CCI, Charlson Comorbidity Index; SpO2, pulse oximetry; mMRC, Modified Medical Research Council.