Table S1.
Cox regression analysis with GOLD severity classification to identify the predictors of mortality in the 9-year period
| Variables | HR (95% CI) N=110 | P-value |
|---|---|---|
|
| ||
| Male | 1.25 (0.64–2.55) | 0.536 |
| Age (years) | 0.98 (0.92–1.03) | 0.465 |
| SpO2 (%) | 0.96 (0.85–1.08) | 0.521 |
| 6MWT (m) | 0.99 (0.99–1.00) | 0.625 |
| BMI >21 kg/m2 | 0.96 (0.91–1.02) | 0.304 |
| GOLD 1 – reference | ||
| GOLD 2 | 1.16 (0.37–3.61) | 0.798 |
| GOLD 3 | 1.63 (0.53–4.99) | 0.390 |
| GOLD 4 | 2.18 (0.63–7.60) | 0.218 |
| mMRC (score) | 1.13 (0.80–1.59) | 0.481 |
| CCI | 1.32 (0.99–1.76) | 0.058 |
| Exacerbation (n) | 1.24 (0.92–1.69) | 0.153 |
Notes: All variables were included together in the Cox proportional hazard regression (sex, age, SpO2, 6MWT, BMI, mMRC, CCI, number of exacerbations in first 3 years, and 2004 GOLD classification of airflow limitation severity). Exacerbation, number of exacerbations per patient in the 3-year period.
Abbreviations: 6MWT, 6-minute walk test; BMI, body mass index; CCI, Charlson Comorbidity Index; SpO2, pulse oximetry; mMRC, Modified Medical Research Council.