Figure 1.

Associations between body mass index (continuous) and metabolite concentrations plotted as –log₁₀ (q-values) in the EPIC-Oxford cohort. The dashed line shows the corrected significance level (False Discovery Rate). The q-values were derived from linear regression adjusted for age (years, continuous), smoking status (never; former; current), the Cambridge index of physical activity (inactive; moderately inactive, moderately active; active), alcohol intake (<1; 1-7; 8-15; ≥16 g/d), diet group (meat eater; fish eater; vegetarian; vegan), batch (categorical), time since last food or drink at blood collection (min, continuous), time between blood collection and processing (fourths of the distribution corresponding to <25; 25-41; 41-72; ≥72h; unknown). The beta coefficient and 95% confidence intervals of metabolite concentrations are shown in Table S2.