Fig 6.

Representative western blots (top) and their quantifications (bottom) assessing differences in striatal levels of Rac1 and WAVE-1 of adult male and female, WT, WAVE-Tg, GluN1KD, and GluN1KD-WAVE mice. WAVE-1 was confirmed to be decreased in GluN1KD mice, increased in WAVE-Tg mice, and attenuated towards WT levels in GluN1KD-WAVE mice. No sex differences were observed for striatal WAVE-1 levels (S1 Table). Rac1 was not found to be significantly different between genotypes. A sample size of 6 mice was used for every genotype. Data was analyzed by one-way ANOVAs followed by Bonferroni post hoc comparisons for all pairings, # p = 0.09, * p < 0.05, ** p < 0.01.