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. 2018 Oct 23;13(10):e0205827. doi: 10.1371/journal.pone.0205827

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© 2018 Lu et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — (A) Cost-Effectiveness Acceptability Curves Comparing the Cost-effectiveness of Crizotinib Treatment with the ALK Rearrangement Testing (NGS and multiplex PCR) Versus Standard Chemotherapy, with PAP; (B) Scatter Plot of Monte Carlo Probabilistic Sensitivity Analysis, NGS vs. Control Strategy, with Patient Assistance Program (PAP); (C) Scatter Plot of Monte Carlo Probabilistic Sensitivity Analysis, Multiplex PCR vs. Control Strategy, with Patient Assistance Program (PAP). Blue line indicates NGS and yellow one is multiplex PCR, ALK: anaplastic lymphoma kinase; NGS: next-generation sequencing; PAP: patient assistance program; QALY: quality-adjusted life-year; PCR: polymerase chain reaction.