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. 2018 Oct 23;8:15631. doi: 10.1038/s41598-018-33926-6

Table 2.

Median and interquartile range (Q1–Q3) of different parameters at different follow-up time in mCNV patients.

T0 T1 T2 p-value a
BCVA (logMAR) 0.6 (0.5–0.8) 0.3 (0.3–0.4)* 0.3 (0.3–0.4) < 0.001
FA Leakage 2 (2–2) 0 (0–0.3) 0.003 b
FA area (mm2) 0.8 (0.5–3) 0.5 (0.3–1.5) 0.005 b
OCTA Selected Area (mm2) 0.9 (0.5–2.9) 0.6 (0.3–2)* 0.5 (0.2–1.5) 0.005
OCTA Flow Area (mm2) 0.5 (0.3–1.5) 0.3 (0.2–0.9)* 0.3 (0.1–0.6) 0.013
CRT (µm) 387.5 (331.0–435.8) 285.0 (257.5–333.5)* 267.0 (255.3–314.5) < 0.001
ELM visualization 0 (0–0) 2 (1.7–2)* 2 (1.8–2) < 0.001
PlGF (pg/ml) 1.8 (1.5–2.9) 1.4 (1.1–1.9)* 0.019 b
VEGF (pg/ml) 3.4 (2–5.6) 0.5 (0.1–0.9)* 0.008 b

BCVA, best corrected visual acuity; FA, fluorescein angiography; OCTA, optical coherence tomography angiography; CRT, central retinal thickness; ELM, external limiting membrane; PlGF, placental growth factor; VEGF, vascular endothelial growth factor.

aFriedman test; bWilcoxon U test.

*p < 0.05 post hoc analysis respect to previous follow-up control.