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. 2018 Oct 23;8:15654. doi: 10.1038/s41598-018-34047-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Acute inhibition of A6 neurons and effect on respiratory responses to activation of central chemoreceptors of conscious adult rats. Summary of data showing the changes in the reflex responses of the fR (A), V_T (B), VE (C), Dia_EMG amplitude (D), number of sighs (E), sigh amplitude (F), active expiration magnitude (G) and active expiration incidence (H; number 1 means that Abd_EMG active expiration is at its maximal value established in each animal during hypercapnia – see Methods) after application of Alst in conscious adult rats in which the LC was transduced with PRSx8-AlstR-GFP-LVV. *p < 0.0001.