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. 2018 Oct 17;12:372. doi: 10.3389/fncel.2018.00372

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Copyright © 2018 Chen, Wang, Zhang, Chen, Yang, Li, Li and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The relative amount of connexin 43 (Cx43) and Toll-like receptor 4 (TLR4) increased after cerebral I/R injury. (A) Photomicrographs showed Cx43 and TLR4 tubulin levels in the sham group and 4 h, 12 h, 24 h, 72 h and 7 days after cerebral I/R injury. (B,C) Quantitative analyses revealed the variation tendency of Cx43 and TLR4 after cerebral I/R injury. (D) Photomicrographs showed Cx43 levels at 24 h after cerebral I/R injury. (E) Quantitative analysis of Cx43. Data represent the mean ± SEM (n = 3 mice/group). *P < 0.05 vs. I/R group.