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. 2018 Oct 17;9:1114. doi: 10.3389/fphar.2018.01114

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Copyright © 2018 Zhang, Nie, Shi, Zhao, Chen, Yao, Sun and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The Wnt/β-catenin signaling pathway and DCU regulatory mechanisms (left) interactions between the Wnt/β-catenin signaling pathway and the Notch signaling pathway, which regulate HF together. (Middle) Wnt/β-catenin signaling pathway and Hippo signaling interaction diagram. Regulate SSC. (Right) Interaction plots of Wnt/β-catenin signaling pathway and TGF-β signaling pathway. It is related to the production of fibroblasts. Wnt/β-catenin participates in the proliferation of fibroblasts, epidermal stem cells, and hair follicle stem cells and promotes DCU healing.