Table 1.

The function of Wnt signaling in molecular biology of DCU.

Wnt pathway-associated protein	Function
Wnt3a	Promotes fibroblast proliferation
β-catenin	Promote epidermal cell proliferation, differentiation, and migration
Wnt7b	Stimulating macrophages
Wnt10b	Stimulate hair follicle development
Wnt5a	Proinflammatory factor
GSK-3β	Inhibition of apoptotic nuclear DNA
C-myc	Stimulating epidermal stem cells