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. 2018 Oct 17;9:1194. doi: 10.3389/fphar.2018.01194

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Copyright © 2018 Saw, Zhang, Nie, Zhang, Xu and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–D) TEM images (A,B) and size distribution (C,D) of the siCypA-loaded NPs without aptide decoration (A,C) and the APT-_EDB NPs (B,D). (E) Size and polydispersity (PDI) of the siCypA-loaded NPs with (APT-_EDB NPs) or without aptide decoration (NPs) incubated in PBS buffer containing 10% FBS for different time. (F) Cumulative siRNA release from the Cy5.5-siCypA-loaded NPs with (APT-_EDB NPs) or without aptide decoration (NPs) incubated in PBS buffer at 37°C.