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. 2018 Oct 17;9:2398. doi: 10.3389/fimmu.2018.02398

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Copyright © 2018 Xue, Zhang, Pan, Du, Zhou, Zhang, Tian, Zhou and Bai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gut microbes inhibit Con A-induced liver injury. (A–D) Mean fluorescence intensity of CD69 in hepatic iNKT cells (A), percentages of IFNγ⁺ hepatic iNKT cells (B), ALT and AST in serum (C), hematoxylin and eosin staining of liver tissues (D) from indicated mice after Con A (15 mg/kg) or A77636 (8 mg/kg) plus Con A injection (n = 10–15 mice per group). Bar, 100 μm. Error bars represent SEM. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. AB, antibiotic; MFI, mean fluorescent intensity; ConA, Concanavalin A; ALT, alanine transaminase; AST, aspartate aminotransferase.