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. 2018 Oct 17;9:2354. doi: 10.3389/fmicb.2018.02354

Table 2.

Applications of BAPs produced by Lactobacillus species depending on the production strategy.

Protein sources Species Activities Reference
Functionalization of food products

Cow milk Lb. helveticus ACE inhibitory Quan et al., 2008; Wakai and Yanamoto, 2012
Cow milk Lb. helveticus Immunomodulation Matar et al., 2001
Cow milk Lb. helveticus Bone mineralization Narva et al., 2004a
Cow milk Lb. casei ACE inhibitory Li et al., 2017
Cow milk Lb. casei Bone mineralization Kim et al., 2009
Camel and cow milk Lb. plantarum, Lb. paraplantarum, Lb. kefiri, Lb. gasseri, Lb. paracasei Antioxidant Soleymanzadeh et al., 2016
Pea Lb. plantarum ACE inhibitory Jakubczyk et al., 2013
Soy milk Lb. plantarum ACE inhibitory, antioxidant Singh and Vij, 2017

Extraction or purification of peptides from fermented products

Cow milk or whey Lb. helveticus ACE inhibitory, antitumoral LeBlanc et al., 2002; Ahtesh et al., 2016
Cow milk Lb. plantarum Antiinflammatory, antihemolytic, antioxidant, antimutagenic, and antimicrobial Aguilar-Toalá et al., 2017
Cow milk Lb. acidophilus, Lb. helveticus, Lb. delbrueckii subsp. bulgaricus ACE inhibitory Gandhi and Shah, 2014
Cow milk Lb. casei, Lb. rhamnosus ACE inhibitory, antioxidant Solieri et al., 2015
Cow milk Lb. paracasei Hypertensive Cheng and Pan, 2017
Cow milk Lb. casei ACE inhibitory Han et al., 2012
Cow milk Lb. delbrueckii subsp. bulgaricus ACE inhibitory, immunomodulation Kliche et al., 2017
Camel and cow milk Lb. plantarum, Lb. reuteri ACE inhibitory, α-glucosidase and α-amylase inhibitory, antioxidant Ayyash et al., 2017
Bovine sodium caseinate Lb. acidophilus Antimicrobial Hayes et al., 2006

Utilization of partially purified CEPs for protein hydrolysis

Bovine β-casein Lb. acidophilus ACE inhibitory Ren et al., 2015
Sodium caseinate (different sources) Lb. helveticus ACE inhibitory Minervini et al., 2003
Cow milk Lb. delbrueckii subsp. lactis ACE inhibitory Gnasegaran et al., 2017

ACE, angiotensin converting enzyme; CEP, cell envelope proteinase.