TABLE 2.

BacCapSeq yields higher read counts and genome coverage than UHTS in whole blood spiked with bacterial cells

Species	Genome length (nt)	Coding region (%)	Load (copies/ml)	Bacterial read counta		Fold increase	Genome coverage (%)
				BacCapSeq	UHTS		BacCapSeq	UHTS
Bordetella pertussis	4,386,396	89	40,000	90,597	136	694	82	9
			4,000	14,858	16	979	39	5
			400	1,622	2	725	13	1
			40	269	1	508	8	0
Klebsiella pneumoniae	5,333,942	89	40,000	148,203	455	339	92	6
			4,000	16,929	40	442	58	1
			400	2,771	5	551	18	0
			40	522	0	NAb	5	0
Mycobacterium tuberculosis	4,411,532	91	40,000	5,801	25	243	46	0
			4,000	845	3	287	9	0
			400	14	0	NA	0	0
			40	6	0	NA	0	0
Neisseria meningitidis	2,272,360	86	40,000	60,480	115	546	90	6
			4,000	6,894	8	908	57	0
			400	1,454	1	1,561	23	0
			40	151	0	NA	6	0
Streptococcus pneumoniae	2,038,615	86	40,000	3,070	6	506	43	0
			4,000	588	1	948	13	0
			400	35	0	NA	1	0
			40	4	0	NA	0	0

^aBacterial reads per 1 million reads are shown without applying a cutoff threshold.

^bNA, not applicable because fold increase was not calculated for results with <1 read.