Table 3.
Predicting response to biologic therapy: improvements in the BASDAI
| Baseline variable | Model 1 (n = 135), coefficient (95% CI) | Model 2 (n = 121), coefficient (95% CI) |
|---|---|---|
| Constant | −0.99 (−2.72, 0.75) | −0.28 (−2.03, 1.48) |
| BASDAI | 0.72 (0.49, 0.95) | 0.84 (0.60, 1.08) |
| BASFI | −0.38 (−0.60, −0.17) | −0.17 (−0.41, 0.07) |
| Age (years) | ||
| <30 | 0 | 0 |
| 30–39 | 0.75 (−0.56, 2.07) | 0.82 (−0.46, 2.10) |
| 40–49 | 0.58 (−0.73, 1.89) | 0.29 (−0.98, 1.56) |
| 50–59 | 0.31 (−1.11, 1.73) | 0.26 (−1.14, 1.66) |
| 60–69 | 0.41 (−1.03, 1.86) | 0.13 (−1.35, 1.62) |
| ≥70 | −1.03 (−3.25, 1.19) | −0.89 (−3.22, 1.43) |
| Index of Multiple Deprivation (quintiles) | ||
| 1 (highest deprivation) | 0 | 0 |
| 2 | 0.58 (−0.71, 1.87) | 0.66 (−0.68, 2.00) |
| 3 | −0.20 (−1.43, 1.03) | −0.50 (−1.79, 0.80) |
| 4 | 0.91 (−0.28, 2.11) | 0.71 (−0.52, 1.94) |
| 5 | 0.55 (−0.67, 1.78) | 0.19 (−1.12, 1.49) |
| Gender | ||
| Male | 0 | 0 |
| Female | −0.61 (−1.38, 0.17) | −0.10 (−0.91, 0.70) |
| Smoking status | ||
| Never | 0 | 0 |
| Ex-smoker | 0.13 (−0.72, 0.98) | 0.21 (−0.64, 1.06) |
| Current | 0.19 (−0.76, 1.13) | 0.59 (−0.40, 1.57) |
| FM criteria met | −0.58 (−1.40, 0.23) | Not applicable |
| FM | Not applicable | |
| WPI | −0.10 (−0.24, 0.03) | |
| SSS | −0.32 (−0.53, −0.12) |
Model 1 fit: R2 = 0.3261; model 2 fit: R2 = 0.4079.