Table 4.
Predicting response to biologic therapy: improvements in QoL (ASQoL score)
| Variable | Model 1 (n = 133), coefficient (95% CI) | Model 2 (n = 119), coefficient (95% CI) |
|---|---|---|
| Constant | −0.93 (−4.72, 2.86) | −0.15 (−3.96, 3.66) |
| ASQOL | 0.30 (0.01, 0.59) | 0.52 (0.20, 0.84) |
| BASDAI | 0.36 (−0.17, 0.89) | 0.52 (−0.03, 1.06) |
| BASFI | −0.50 (−1.06, 0.06) | −0.23 (−0.82, 0.35) |
| Age (years) | ||
| 30–39 | 2.37 (−0.46, 5.21) | 2.31 (−0.46, 5.08) |
| 0–49 | 2.16 (−0.71, 5.03) | 1.75 (−1.03, 4.53) |
| 50–59 | 0.93 (−2.20, 4.07) | 1.01 (−2.07, 4.09) |
| 60–69 | 0.90 (−2.30, 4.10) | 0.49 (−2.74, 3.72) |
| ≥70 | 0.82 (−3.99, 5.62) | 1.60 (−3.42, 6.63) |
| Index of Multiple Deprivation (quintiles) | ||
| 1 (highest deprivation) | 0 | 0 |
| 2 | −1.27 (−4.05, 1.51) | −0.45 (−3.35, 2.46) |
| 3 | −1.28 (−3.97, 1.42) | −1.01 (−3.85, 1.83) |
| 4 | 0.77 (−1.80, 3.35) | 0.95 (−1.71, 3.61) |
| 5 | −0.40 (−3.04, 2.24) | −0.61 (−3.42, 2.20) |
| Gender | ||
| Female | −0.67 (−2.37, 1.04) | 0.17 (−1.60, 1.94) |
| Smoking status | ||
| Never | 0 | 0 |
| Ex-smoker | 1.31 (−0.55, 3.17) | 1.33 (−0.51, 3.18) |
| Current | 0.43 (−1.72, 2.57) | 0.72 (−1.48, 2.92) |
| FM criteria met | −0.51 (−2.29, 1.26) | Not applicable |
| FM | Not applicable | |
| WPI | −0.19 (−0.49, 0.10) | |
| SSS | −0.74 (−1.22, −0.25) |
Model 1 fit: R2 = 0.1830; model 2 fit: R2 = 0.2896.