Figure 4. KT2 affects the expression of apoptosis-related proteins in HCT116 cell xenografts. After treatment, tumors were isolated from HCT116cell xenografts and western blotting was performed as described in the Materials and Methods for β-actin, BCL2 apoptosis regulator (BCL2),BCL2-associated X (BAX), caspase-3 and poly (ADP-ribose) polymerase (PARP). PBS: Phosphate-buffered saline. The numbers under the gelelectrophoresis were calculated from the normalization ratio of compound band density/beta-actin hand density.