Table 1.
IC50 values of SCH772984 and MEK162 in parental and resistant cells
| IC50 MEK162 (nM) | RI | IC50 SCH772984 (nM) | RI | |
|---|---|---|---|---|
| H727 | 115 | – | 135 | – |
| H727-MEK | > 1000 | > 9 | > 1000 | > 9 |
| H727-SCH | > 1000 | > 9 | > 1000 | > 9 |
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