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. 2018 Dec;13(12):2191–2199. doi: 10.4103/1673-5374.241473

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Copyright: © Neural Regeneration Research

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Effects of lithium and 3-MA on motor function in rats with SCI.

The BBB locomotor rating scale scores ranged from 0 to 21 points. Lower scores indicate poorer motor function. BBB scores were significantly higher in the lithium group than in the SCI and 3-MA groups at 1, 2, 3 and 4 weeks after SCI (P < 0.05). There was no difference in BBB scores between the 3-MA group and the SCI group at 1 or 2 weeks after SCI, while BBB scores were higher in the 3-MA group than in the SCI group (P < 0.05). *P < 0.05, vs. SCI group; #P < 0.05, vs. 3-MA group (mean ± SD, n = 6; one-way analysis of variance followed by the least significant difference post hoc test). BBB: Basso, Beattie & Bresnahan; 3-MA: 3-methyladenine; SCI: spinal cord injury; h: hours; W: week(s).