Table 2.
Minimum Inhibitory Concentrations of Various Standard Antimicrobials Against Clinical Strains of Mycobacterium chelonae Recovered from Patients with Cystic Fibrosis
| Antibiotic | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Isolate number | CLA | SXT | CIP | MXF | FOX | AMI | TGC | LZD | IMI | FEP | AUG | AXO | MIN | TOB | CFZ | DAP | RIF | RBT |
| 52 | 16 | >8/152 | 2 | 4 | 128 | 32 | 1 | 16 | 16 | 32 | >64/32 | >64 | >8 | 16 | 3 | 1.5 | >8 | >8 |
| 53 | 16 | >8/152 | >4 | >8 | >128 | 64 | 1 | 32 | 32 | >32 | >64/32 | >64 | >8 | 16 | 0.375 | 1.5 | >8 | >8 |
| 54 | 16 | 2/38 | 1 | 2 | >128 | 16 | 0.25 | 2 | 8 | >32 | 64/32 | >64 | >8 | 16 | 1.5 | 1.5 | >8 | >8 |
| 55 | 8 | >8/152 | 4 | 8 | >128 | 64 | 1 | 32 | 32 | >32 | >64/32 | >64 | >8 | 16 | ND | ND | >8 | >8 |
| 56 | 1 | 8/152 | >4 | 8 | >128 | 64 | ND | 16 | 16 | ND | ND | ND | >8 | 4 | 0.75 | 0.75 | >8 | >8 |
Shaded cells indicate resistant (medium gray), intermediate (light gray), or susceptible (dark gray) minimum inhibitory concentrations based on current CLSI guidelines.11 Unshaded cells are those for which no interpretations have been established.
AMI, amikacin; AUG, augmentin; AXO, ceftriaxone; CFZ, clofazimine; CIP, ciprofloxacin; CLA, clarithromycin; trimethoprim/sulfamethoxazole; DAP, dapsone; FEP, cefipime; FOX, cefoxitin; IMI, imipenem; LZD, linezolid; MIN, minocycline; MXF, moxifloxacin; ND, not done; RBT, rifabutin; RIF, rifampin; SXT, trimethoprim/sulfamethoxazole; TGC, tigecycline; TOB, tobramycin.