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Caspase-3 activity in tumoral and nontumoral tissue.
Notes: Caspase-3 activity was lower in tumoral and nontumoral tissues in the treated groups; as shown, a slight but nonsignificant reduction in caspase-3 activity was found in tumor of animals after administration of salirasib and/or sorafenib (n=16) compared with DMSO control group (n=6) (P=0.154; NS).
Abbreviations: DMSO, dimethyl sulfoxide; NS, not significant.
