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. 2018 Oct 24;13(10):e0202297. doi: 10.1371/journal.pone.0202297

Fig 3. Role of irbesartan pre-treatment on inflammatory mediators and on cytokines activity.

Fig 3

(A) iNOS TNF-alpha and IL-17 proteins expressions were measured by western blot. GAPDH was used as internal standard. Representative blot from three independent experiments. Data are expressed as relative densitometric units and represent the mean ± S.E.M. of three independent experiments (*P<0.05 versus CTRL; #P<0.05 versus hypoxia, § P<0.05 versus irbesartan 10 μM). (B) TNF-alpha and (C) IL-17 activity was measured by ELISA. Final concentration of each cytokine was expressed as pg/mg and represent the mean ± S.E.M. of three independent experiments (*P<0.05 versus CTRL; #P<0.05 versus hypoxia).