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. 2018 Oct 24;13(10):e0205147. doi: 10.1371/journal.pone.0205147

Table 1. Results of the trend analysis for the 27 indicators of the synthetic regional reports for the period 2014–2016, and evaluation of target achievements.

Indicator WHO Target Well-performing
Regions*
N (%)
Improving
Regions**
N (%)
Regions with
no data
available***
N (%)
Routine vaccination coverage
    Measles-containing vaccine. 1st dosea ≥95% 0 (0.0) 11 (52.4) 0 (0.0)
    Measles-containing vaccine. 2nd dosea ≥95% 0 (0.0) 7 (33.3) 0 (0.0)
    Rubella-containing vaccine. 1st dosea ≥95% 0 (0.0) 11 (52.4) 0 (0.0)
    Rubella-containing vaccine. 2nd dosea ≥95% 0 (0.0) 7 (33.3) 0 (0.0)
Incidence or number of cases
    Measles incidence per 1 million populationb <1 case / 1,000,000 3 (14.3) 11 (52.4) 0 (0.0)
    Rubella incidence per 1 million populationb <1 case / 1,000,000 17 (81.0) 2 (9.5) 0 (0.0)
    Number of CRS casesc <1 case / 100,000 20 (95.2) 0 (0.0) 0 (0.0)
Epidemiological investigation of measles cases
    Percentage of lab-confirmed cases 9 (42.9) 3 (14.3)
    Percentage of cases with unknown vaccination statusd 11 (52.4) 3 (14.3)
    Percentage of measles cases with genotype information 4 (19.0) 11 (52.4)
Epidemiological investigation of rubella cases
    Percentage of lab-confirmed cases 1 (4.8) 13 (61.9)
    Percentage of cases with unknown vaccination statusd 6 (28.6) 13 (61.9)
Outbreaks and Supplemental Immunization Activities (SIAs)
    Number of outbreakse 15 (71.4) 0 (0.0)
    Percentage of outbreaks with genotype information 10 (47.6) 6 (28.6)
    Percentage of outbreaks with submission of the outbreak reporting form 5 (23.8) 6 (28.6)
    Percentage of outbreak reporting forms with description of outbreak and measures taken 6 (28.6) 6 (28.6)
    Number of SIAsf 5 (23.8) 0 (0.0)
Performance of measles surveillance
    Timeliness of reporting ≥80% 17 (81.0) 2 (9.5) 0 (0.0)
    Completeness of reporting ≥80% 17 (81.0) 2 (9.5) 0 (0.0)
    Rate of laboratory investigations ≥80% 2 (9.5) 3 (14.3) 1 (4.8)
    Rate of discarded casesg ≥2 discarded cases /
100,000 population
0 (0.0) 2 (9.5) 0 (0.0)
    Origin of infection identified ≥80% 14 (66.7) 0 (0.0) 3 (14.3)
Performance of rubella surveillance
    Timeliness of reporting ≥80% 17 (81.0) 2 (9.5) 0 (0.0)
    Completeness of reporting ≥80% 17 (81.0) 2 (9.5) 0 (0.0)
    Rate of laboratory investigations ≥80% 4 (19.0) 1 (4.8) 7 (33.3)
    Rate of discarded casesg ≥2 discarded cases /
100,000 population
0 (0.0) 3 (14.3) 0 (0.0)
    Origin of infection identified ≥80% 7 (33.3) 0 (0.0) 11 (52.4)
Total 21 (100) 21 (100) 21 (100)

Notes

* (only for indicators with WHO targets): Regions that have either maintained for the period considered, or achieved at the end of that period, the relative WHO target.

**: Regions that have improved over the period considered in accordance with the definition of improvement given to each indicator (see notes a-g).

***: Regions with no data available, i.e. Regions for which the indicator in question could not be evaluated due to the unavailability of data for either two or all of the three years considered.

a: Improvement is defined as a ≥0.5 percentage point increase in vaccination coverage in the last year available, compared to the first year.

b: Improvement is defined as a decrease of ≥1 case per 1 million population in the incidence of measles/rubella in the last year available, compared to the first year.

c: Improvement is defined as a decrease of ≥1 case in the number of CRS cases notified in the last year available, compared to the first year.

d: Improvement is defined as a ≥1 percentage point decrease in the percentage of cases with unknown vaccination status in the last year available, compared to the first year; Regions are also considered to be improving if 0 cases with unknown vaccination status were reported in both years.

e: Improvement is defined as a ≥1-point reduction in the number of outbreaks notified in the last year available, compared to the first year; Regions are also considered to be improving if 0 outbreaks were reported in both years.

f: Improvement is defined as a ≥1-point increase in the number of SIAs reported in the last year available, compared to the first year.

g: Improvement is defined as a ≥0.2 percentage point increase in the rate of discarded cases in the last year available, compared to the first year.

For all remaining indicators, improvement is defined as a ≥1 (percentage) point increase in the rate/percentage registered in the last year available, compared to the first year.