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. 2018 Oct 24;13(10):e0205788. doi: 10.1371/journal.pone.0205788

Table 2. Quantification of 16S copies in culture-negative, culture-positive, and respiratory tract flora (RTF) for bronchoalveolar lavage (BAL) samples.

Patients who were on antibiotics at the time of BAL are denoted with an asterisk next to BAL ID #. Pathology results are the results of BAL which were used for treatment clinically. Copy number of 16S is denoted at copies per microliter +/- standard error of the mean (SEM).

BAL ID # Pathology Lab Results VAP Inflammation No Inflammation 16S Copies/μl ± SEM
No VAP NoVAP
186 No growth No No Yes 24,266 ± 624
189* No growth No Yes No 21,840 ± 706
196 No growth No No Yes 10,860 ± 1,244
197* No growth No Yes No 6,160 ± 136
201* No growth No No Yes 252,533 ± 9,534
209* No growth No Yes No 134,000 ± 5,108
260* No growth No No Yes 67,533 ± 7,720
184 >100,000 S. aureus, >100,000 S. pneumoniae Yes No No 413,000 ± 9,035
195* >100,000 Citrobacter koseri, 40,000 P. aeruginosa Yes No No 912,000 ± 24,248
204 >100,000 Streptococci (NOT S. pneumoniae or Enterococcus) Yes No No 78,666 ± 2,130
204B >100,000 Pseudomonas, >100,000 Enterobacter spp., 100,000 RTF Yes No No 6,789,333 ± 202,403
206 >100,000 H. influenza, light RTF Yes No No 669,200 ± 20,047
221 >100,000 M. catarrhalis, 20,000 K. pneumoniae Yes No No 434,600 ± 16,985
226 >100,000 Acinetobacter baumannii/ haemolyticus, >100,000 RTF No Yes No 134,200 ± 3,113
185 60,000 RTF No Yes No 836,000 ± 42,755
211 50,000 RTF No No Yes 725,800 ± 4,331
224 30,000 RTF No Yes No 209,600 ± 7,480
229 50,000 RTF No Yes No 476,400 ± 2,271
246* 3,000 RTF No Yes No 110,933 ± 7,968
249 2,000 RTF No Yes No 706,000 ± 14,089
254 4,000 RTF No Yes No 174,666 ± 5,484
255 30,000 RTF No Yes No 53,400 ± 6,293