Skip to main content
. Author manuscript; available in PMC: 2019 Oct 3.
Published in final edited form as: J Am Chem Soc. 2018 Sep 19;140(39):12415–12423. doi: 10.1021/jacs.8b05143

Table 2.

Impact of Additives on the Arylation of Toluenea

graphic file with name nihms-990070-t0020.jpg
entry base additives equiv yield (%)b
1 KN(SiMe3)2 – – 93
2 KN(SiMe3)2 18-crown-6 1.5 64
3 KN(SiMe3)2 18-crown-6 3.0 20
4 KN(SiMe3)2 15-crown-5 1.5 35
5 KN(SiMe3)2 15-crown-5 3.0 10
a

Reaction conducted on a 0.1 mmol scale

b

Yield determined by 1H NMR spectroscopy of the crude reaction mixture.