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. 2018 Oct 5;97(40):e12441. doi: 10.1097/MD.0000000000012441

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Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0

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^99mTc-PEG4-E[PEG4-c(RGDfK)]2 (^99mTc-3PRGD2) single-photon emission computed tomography/computed tomography (SPECT/CT) images (axial, sagittal, and coronal) and CDFI images before and 3 months after PB treatment in a 78-year-old woman with choroidal melanoma (CM) (patient 7). Intense accumulation of ^99mTc-3PRGD2 in the lesion in the right eye (red cross) fell from tumor-to-occipital bone ratio (T/O) = 5.13, normal tissue-to-occipital bone ratio (N/O) = 0.91 before PB to T/O = 2.62, N/O = 0.74 at 3 months post-PB. B-mode ultrasonography and CDFI showed that the base length and height of the lesion varied from 14.1 and 13.7 mm, respectively (before treatment) to 13 and 15.4 mm, respectively at 3 months post-PB. CDFI = color Doppler flow imaging, CT = computed tomography, PB = plaque brachytherapy.