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. Author manuscript; available in PMC: 2019 Oct 29.
Published in final edited form as: Vaccine. 2018 Sep 25;36(45):6744–6751. doi: 10.1016/j.vaccine.2018.09.031

Fig. 4. Increase in HA-specific antibody levels following immunization with HAd-H5HA with a decline in vector immunity with time.

Fig. 4.

At 1, 3, 6, and 10 months post-HAd-GFP inoculation, naïve or HAdV-primed BALB/c mice were immunized i.m. with 108 PFU of HAd-H5HA, and at 4 weeks after the immunization with HAd-H5HA, the blood samples were collected to monitoring the development of HA-specific antibody levels by ELISA. ns, non-significant at p<0.05; *, significant at p<0.05; and ****, significant at p<0.0001. The statistical analysis was done by Bonferroni post-test and two-way ANOVA using GraphPad Prism 6.